Great Smokies Medical Center of Asheville

Signs and Symptoms of Specific Nutrient Deficiencies

The following nutrient deficiencies are related to the listed signs and symptoms:

Fat-soluble Vitamins
Vitamin A: Increased susceptibility to cancer, acne, night blindness and other eye problems; impaired maintenance, repair, and healing of skin and mucus membranes; impaired bone and teeth formation; accelerated aging
Vitamin D: (Rickets) Bone loss (osteoporosis); low blood calcium; osteomalacia (pain in ribs, spine, pelvis, legs, muscle weakness, brittle bones); retarded growth; muscle weakness, impaired tooth development; rickets in children
Vitamin E: Susceptibility to cancer and heart disease; anemia; lethargy; apathy; inability to concentrate; muscle weakness; decreased sexual performance
Vitamin K: Impaired blood clotting

Water-soluble Vitamins
Vitamin B1 (Thiamine): (Beriberi) Impairment of gastric acid production, blood formation, circulation, and starch metabolism; gastrointestinal, neurological, and heart muscle tone problems, learning and growth; low energy
Vitamin B2 (Riboflavin): Impaired metabolism of carbohydrates, fats and proteins; impaired cell growth and production of antibodies; tired eyes; cataracts; sores and cracks in corners of the mouth; decreased iron and pyridoxine levels
Vitamin B3 (Niacin): (Pellagra) The three D’s: dermatitis, dementia and diarrhea; circulatory problems; heart disease
Vitamin B5 (Pantothenic Acid): headache, listlessness, fatigue, insomnia, intestinal disturbances, and numbness and tingling of hands and feet
Vitamin B6 (Pyridoxine): Fatigue; carpal tunnel syndrome; water retention; irritability; increased premenstrual stress; allergies; asthma; weakened immune system; heart disease
Vitamin B12 (Hydroxycobalomin): Anemia; improper digestion and metabolism of foods; nerve damage; fatigue; uneven gait; infertility; memory loss; cataracts
Folic Acid: Fatigue, anemia, weakness and low energy; problems with clotting and bruising; birth defects; cervical dysplasia; elevated homocysteine level (a risk factor in heart disease)
Vitamin C (Ascorbic Acid): Weakened immune system; increased susceptibility to cancer; impaired wound healing; gum disease; damage to nerves, eyes and vascular system; bruising

Minerals
Calcium: Osteoporosis; muscle cramps; joint aches; increased cholesterol levels; nervousness; heart rhythm irregularities; skin disorders; brittle nails; rheumatoid arthritis; tooth decay; sleep disturbances; numbness in arms and/or legs; rickets
Magnesium: Muscle weakness and twitching (spasm); depression; dizziness; high blood pressure; heart disease and cardiac arrhythmias; asthma; menstrual cramps
Phosphorus: Mineral imbalance, especially calcium and magnesium; impaired bone and teeth formation; kidney function; heart muscle contraction problems
Potassium: Heart irregularities; increased blood pressure; muscle twitches; weakness; fluid imbalances

Trace Minerals
Chromium: Poor glucose/insulin control.
Copper: Fatigue; impaired wound healing; osteoporosis; altered sense of taste
Iodine: Lethargy, constipation, dry skin
Iron: Anemia; fatigue; weakness and low energy; clotting and bruising problems
Selenium: Increased susceptibility to cancers of liver, skin, breast and colon; stroke; heart muscle disorders; immune system deficiencies; allergy
Sodium: Fluid and electrolyte imbalance, weakness and fatigue
Vanadium: Poor glucose/insulin regulation.
Zinc: Impaired wound healing; weakened immune system; impaired sense of smell and taste.

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